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. 2021 Sep;9(18):1437. doi: 10.21037/atm-21-4227

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2021 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Kaplan-Meier curves of patients with five cancer types after ICI treatment, stratified by top tertile TMB value. (A) Cholangiocarcinoma, (B) nervous system tumor, (C) gastric cancer, (D) hepatocellular carcinoma, (E) colorectal cancer. Patients with TMB values in the top tertile were defined as the TMB-high group and the patients in the other two tertiles were defined as the TMB-low group. P value was obtained from two-sided log-rank test. TMB, tumor mutational burden; ICI, immune checkpoint inhibitor.