Table 2. Base-case scenario results.
Life year (years) | Total cost ($) | Cost in PFS ($) | Cost in PP ($) | Cost in terminal ($) | QALY | QALY in PFS | QALY in PP | Increase cost-effectiveness ratio ($/QALY) | |
---|---|---|---|---|---|---|---|---|---|
Discount =3% | |||||||||
Docetaxel | 1.415569 | 33,086.801 | 16,584.98243 | 13,985.57082 | 2,516.248171 | 0.699023008 | 0.415285922 | 0.283737086 | |
Pembrolizumab 2 mg/kg | 2.506085 | 87,134.788 | 65,950.3899 | 18,731.75113 | 2,452.646488 | 1.200180446 | 0.820153592 | 0.380026854 | 107,846.3214 |
Pembrolizumab 10 mg/kg | 3.268327 | 369,326.82 | 341,301.0169 | 25,622.14013 | 2,403.662537 | 1.448864396 | 0.929046401 | 0.519817995 | 448,414.8563 |
Discount =0 | |||||||||
Docetaxel | 1.586283 | 35,962.074 | 16,848.39896 | 16,494.32379 | 2,619.351697 | 0.756516116 | 0.42188184 | 0.334634276 | |
Pembrolizumab 2 mg/kg | 2.608329 | 100,049.463 | 75,925.75792 | 21,508.11567 | 2,615.589261 | 1.380579307 | 0.944226001 | 0.436353306 | 102,693.7485 |
Pembrolizumab 10 mg/kg | 3.407474 | 433,056.416 | 399,721.7948 | 30,732.713 | 2,601.908083 | 1.71157748 | 1.088076977 | 0.623500503 | 415,778.8773 |
PFS, progression-free survival; PP, post-progression; QALY, quality-adjusted life year.