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. 2021 Sep;9(18):1480. doi: 10.21037/atm-21-4178

Table 2. Base-case scenario results.

Life year (years) Total cost ($) Cost in PFS ($) Cost in PP ($) Cost in terminal ($) QALY QALY in PFS QALY in PP Increase cost-effectiveness ratio ($/QALY)
Discount =3%
   Docetaxel 1.415569 33,086.801 16,584.98243 13,985.57082 2,516.248171 0.699023008 0.415285922 0.283737086
   Pembrolizumab 2 mg/kg 2.506085 87,134.788 65,950.3899 18,731.75113 2,452.646488 1.200180446 0.820153592 0.380026854 107,846.3214
   Pembrolizumab 10 mg/kg 3.268327 369,326.82 341,301.0169 25,622.14013 2,403.662537 1.448864396 0.929046401 0.519817995 448,414.8563
Discount =0
   Docetaxel 1.586283 35,962.074 16,848.39896 16,494.32379 2,619.351697 0.756516116 0.42188184 0.334634276
   Pembrolizumab 2 mg/kg 2.608329 100,049.463 75,925.75792 21,508.11567 2,615.589261 1.380579307 0.944226001 0.436353306 102,693.7485
   Pembrolizumab 10 mg/kg 3.407474 433,056.416 399,721.7948 30,732.713 2,601.908083 1.71157748 1.088076977 0.623500503 415,778.8773

PFS, progression-free survival; PP, post-progression; QALY, quality-adjusted life year.