Table 1. Negatively regulated miRNA-gene pairs in PCOS (PNA mice compared with the control mice).
miRNA | Log2FC | Expression change | Target gene | Log2FC | Expression change |
---|---|---|---|---|---|
miR-106a-5p | −1.72 | Down | Cd28 | 8.39 | Up |
Il10rb | 2.25 | Up | |||
Stat3 | 1.36 | Up | |||
Vegfa | 1.09 | Up | |||
miR-155-5p | −1.14 | Down | Arntl | 1.30 | Up |
Gsk3b | 2.04 | Up | |||
S1pr1 | 1.14 | Up | |||
Nr1h3 | 2.60 | Up | |||
Lpin1 | 2.22 | Up | |||
Maf | 3.74 | Up | |||
Trp53inp1 | 1.04 | Up | |||
miR-184-3p | −1.07 | Down | Fzd4 | 1.08 | Up |
PCOS, polycystic ovary syndrome; PNA, prenatally androgenized.