Figure 3.

Downregulation of ACSL4-mitigated sev-induced cell injury in SH-SY5Y cells. (A) si-ACSL4 or si-NC was transfected into SH-SY5Y cells and incubated for 24 h. Following treatment with 4.1% sev for 6 h, SH-SY5Y cells were subjected to qRT-PCR and western blot assays. (B) Cell viability was also examined using a CCK-8 assay. **, P<0.01; ***, P<0.001. ACSL4, acyl-CoA synthetase long chain family member 4; sev, sevoflurane; qRT-PCR, quantitative reverse transcription-polymerase chain reaction; CCK-8, Cell Counting Kit-8.