Table 2. Best tumor responses of patients with low and high baseline HBV DNA level.
| Tumor response | All patients (n=86), n (%) | Baseline HBV DNA <2,000 IU/mL (n=55), n (%) | Baseline HBV DNA ≥2,000 IU/mL (n=31), n (%) |
|---|---|---|---|
| CR | 1 (1.2) | 1 (1.8) | 0 |
| PR | 28 (32.5) | 18 (32.7) | 10 (32.2) |
| SD | 33 (38.4) | 18 (32.7) | 15 (48.4) |
| PD | 24 (27.9) | 18 (32.7) | 6 (19.4) |
| ORR (CR + PR)Δ | 29 (33.7) | 19 (34.5) | 10 (32.2) |
| DCR (CR + PR + SD)* | 62 (72.1) | 37 (67.3) | 25 (80.6) |
Δ, Pearson χ2=0.046, P=0.829; *, Pearson χ2=1.762, P=0.184. CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; ORR, objective response rate; DCR, disease control rate.