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Representative histological frontal sections from the middle regions of the developing palate at different gestation days (H&E staining, ×100). (A) At GD13.5, the palatal shelves exhibited distinct shapes along the AP axis; (B) at GD14.5, the palatal shelves had elevated to the horizontal position; (C) at GD15.5, the palatal shelves had fused at the middle region with complete removal of the midline epithelial seam. N, nose; P, palate; T, tongue; GD, Gestation days.
