Table 4. Multivariate Cox regression analysis for the overall survival and relapse-free survival of CRC patients.
| Characteristics | OS† | RFS‡ | |||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| CA19-9 elevation (vs. normal range) | 3.853 (1.514–9.809) | 0.005 | 1.459 (0.677–3.144) | 0.335 | |
| pT category, pT4 (vs. pT1–pT3) | 2.492 (1.021–6.080) | 0.045 | 1.391 (0.672–2.878) | 0.374 | |
| Distant metastasis, presence (vs. absence) | 2.058 (0.667–6.348) | 0.209 | 30.143 (12.515–72.603) | <0.001 | |
†, variables considered in multivariate analysis for overall survival were CEA elevation, CA19-9 elevation, T stage, lymph node metastasis, distant metastasis, stage. ‡, variables considered in multivariate analysis for relapse-free survival were CEA elevation, CA19-9 elevation, TILs, T stage, lymph node metastasis, distant metastasis, stage, and PIK3CA mutation. CA19-9, cancer antigen 19-9; CI, confidence interval; CRC, colorectal cancer; HR, hazard ratio; OS, overall survival; RFS, relapse-free survival.