Table 1.
The echocardiographic parameters and heart rates at the end of the second and sixth weeks
| Group | EF% | FS% | LAD (mm) | LVID (mm) | LVEDV (uL) | HR (bpm) |
|---|---|---|---|---|---|---|
| Control | 70.17±1.66 | 41.04±1.67 | 4.01±0.07 | 7.86±0.08 | 341.8±11.03 | 333±6 |
| ISO | 43.34±1.71* | 28.77±1.03* | 4.78±0.06* | 8.33±0.1* | 394.38±4.78* | 355±9* |
| Control | 69.37±1.37 | 40.01±1.97 | 4.22±0.08 | 8.17±0.19 | 369.7±9.31 | 339±7 |
| ISO | 40.07±1.87* | 26.21±1.68* | 4.97±0.08* | 8.81±0.12* | 422.6±7.37* | 377±6* |
| Dapa | 60.56±1.73# | 36.04±1.72# | 4.28±0.04# | 8.29±0.12# | 341.8±10.37#,$ | 356±6# |
| S/V | 63.58±0.97# | 38.42±1.33# | 4.24±0.06# | 8.39±0.18# | 382.0±6.42# | 358±10 |
ISO: isoproterenol; S/V: sacubitril/valsartan; Dapa: dapagliflozin; EF: ejection fraction; FS: fractional shortening; LAD: left atrial diameter; LVID: left ventricular internal diameter; LVEDV: left ventricular end-diastolic volume; HR: heart rate.
*
P<0.05 vs. Control;
#
P<0.05 vs. ISO;
$
P<0.05 vs. S/V.