Table 2.

Clinicopathologic characteristics of patients with AML based on the protein expression levels of CDC45 and MCM7

Clinicopathologic characteristic	Total	CDC45				MCM7
		high expression	low expression	χ2	P-value	high expression	low expression	χ2	P-value
Age (year)
<50	86	20	66			27	59
≥50	34	6	28	0.182	0.669	10	24	0.045	0.994
Gender
Male	76	17	59			21	55
Female	44	9	35	0.061	0.806	16	28	0.629	0.428
WBC counts (×109/L), n (%)
<10	35	14	21			17	18
≥10	85	12	73	8.319	0.004**	20	65	6.163	0.013*
Hemoglobin (g/dL), n (%)
<80	69	9	60			15	54
≥80	51	17	34	5.968	0.015*	23	28	6.354	0.012*
Platelet count (×1012/L), n (%)
<50	65	9	56			12	53
≥50	55	17	38	4.155	0.042*	25	30	8.952	0.003**
BM blasts, n (%)
<50	54	18	36			23	31
≥50	66	8	58	6.674	0.009**	14	52	5.403	0.021*
FAB subtype
M1/M2	51	11	40			17	34
M4/M5	69	15	54	0.041	0.841	20	49	0.096	0.757
Cytogenetics
Favorable	35	7	28			19	16
Intermediate	58	14	44			12	46
Unfavorable	27	5	22	0.032	0.859	6	21	5.248	0.022*
Extranmedullary disease
Absent	69	14	55			21	48
Present	51	12	39	0.041	0.839	16	35	0.0081	0.928
Complete Remission
Yes	72	22	50			25	47
No	48	4	44	7.122	0.008**	22	26	1.062	0.303

^*presents P<0.05;

^**presents P<0.01.