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. 2021 Sep 15;13(9):10562–10569.

Table 1.

Association between micropapillary/solid component and clinicopathological characteristics of patients with stage IA lung adenocarcinoma

Characteristics Group P

MP- & SD- MP+/SD+ MPp/SDp
Age (%) 0.064
    ≤60 168 (51.9) 44 (61.1) 9 (34.6)
    >60 156 (48.1) 28 (38.0) 17 (65.4)
Sex 0.205
    male 128 (39.5) 34 (47.2) 14 (53.8)
    female 196 (60.5) 38 (52.8) 12 (46.2)
Tumor size 0.012
    ≤2 cm 276 (85.2) 51 (70.8) 20 (76.9)
    >2 cm 48 (14.8) 21 (29.2) 6 (23.1)
STAS <0.001
    - 312 (96.3) 41 (56.9) 19 (73.1)
    + 12 (3.7) 31 (43.1) 7 (26.9)
LVI 0.160
    - 321 (99.1) 70 (97.2) 25 (96.2)
    + 3 (0.9) 2 (2.8) 1 (3.8)
Predominant subtybe <0.001
    lepidic 21 (6.5) 0 0
    acinar 129 (39.8) 33 (45.8) 0
    papillary 174 (53.7) 39 (54.2) 0
    micropapillary 0 0 15 (57.7)
    solid 0 0 11 (42.3)
Surgery 0.167
    lobectomy 295 (91.0) 70 (97.2) 25 (96.2)
    segmentectomy/wedge resection 29 (9.0) 2 (2.8) 1 (4.0)

CI, confidence interval. HR, hazard ratio. MP- & SD- (both micropapillary and solid component were absent), MP+/SD+ (either micropapillary or solid component was present, but the single or combined percentage of the MP and SD was not greater than 50%), MPp/SDp (either micropapillary or solid or the combined percentage of these two components was great than 50%). STAS, spread through air space.