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. 2021 Sep 20;13(18):22345–22360. doi: 10.18632/aging.203542

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Copyright: © 2021 Yan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Gene Significance (GS) and module membership (MM) were calculated with Pearson correlation analysis. (A) The GS and MM are highly correlated in red (cor = 0.77, P = 1e-09), blue (cor = 0.94, P = 1e-200), brown (cor = -0.85, P = 1e-200) and cyan (cor = -0.91, P = 1e-200) module, indicated that the red and blue module contain genes that have high positive correlation with aSAH while the brown and cyan module contain genes that high negative correlations with aSAH. (B) The GS of aSAH group in red (*: p < 0.01) and blue (***: P < 0.0001) module were significantly higher than control group, while the opposite result was shown in the brown (**: P < 0.001) and cyan module (***: P < 0.0001).