Table 2. Detailed patient information for the three colorectal cancer datasets used to corroborate our analysis.
Datasets | GSE115513 | GSE41655 | GSE71008 |
Number of miRNAs available | 2006 | 851 | 421 |
Patient nationality | USA | China | USA |
Platform | Agilent-046064 Unrestricted Human miRNA V19.0 Microarray | Agilent-021827 Human miRNA Microarray | Illumina Genome Analyzer |
Tissue type | Paired tumour and normal tissue | Tumour and normal tissue | Plasma microvesicles |
Number of samples | |||
Tumour | 750 (54%) | 33 (69%) | 100 (67%)* |
Normal | 649 (46%) | 15 (31%) | 50 (33%)* |
Age (mean ± SD1 years) | |||
Tumour sample patients | 65 ± 11 | 63 ± 11 | 55 ± 18 |
Normal sample patients | 65 ± 11 | 48 ±14 | 54 ± 14 |
Gender | |||
Female | 667 (48%) | 16 (33%) | 74 (49%) |
Male | 732 (52%) | 32 (67%) | 76 (51%) |
Tumour Site | |||
Colon | 792 (57%) | - | - |
Rectum | 607 (43%) | - | - |
1 – standard deviation.
“-“– unspecified.
“*”– Tumour = cancerous patient samples; Normal = healthy individual samples.