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. 2021 Sep 24;13(18):22490–22501. doi: 10.18632/aging.203559

Figure 6.

Figure 6

Schema illustrating the effects of nesfatin-1 upon IL-1β synthesis during OA progression. Nesfatin-1 promotes IL-1β synthesis in human OASFs by suppressing miR-204-5p synthesis in the PI3K, Akt, AP-1 and NF-κB signaling pathways.