Figure 2.

Upregulation of Foxo3 promotes OC cell migration and invasion. (A) Migration ability of SKOV3 cells with Foxo3 knockdown or overexpressing, as determined by wound healing assay. Scale bar = 200 μm. (B) Migration ability of SKOV3 cells with Foxo3 knockdown or overexpressing, as determined by Transwell migration assay. Scale bar = 50 μm. (C) Invasion ability of SKOV3 cells with Foxo3 knockdown or overexpressing, as determined by Transwell invasion assay. Scale bar = 50 μm. Data were expressed as means ± standard deviation. For each treatment, three replicates were used. ^*p < 0.05, ^***p < 0.001.