Fig. 5.

MiR-279-3p-inhibitor-injected DS-strain mosquitoes are more resistant to deltamethrin. a Relative expression of miR-279-3p was decreased by 40.2% in the DS-strain mosquitoes at 72 h after injection with the miR-279-3p inhibitor. b The relative expression of CYP325BB1 was 1.28-fold higher in the DS-strain mosquitoes at 72 h after injection with the miR-279-3p inhibitor. c Mortality under 7 mg/l deltamethrin treatment of the miR-279-3p inhibitor-injected group ranged from 14.9 to 21.3% at 90–120 min in the CDC bottle bioassay, which was lower than that in the acetone control, control and NC1 groups. Data are representative of three technical replicates of biological replicates and are reported as the mean ± SEM. Asterisks indicate significant difference at *P < 0.05, **P < 0.01, ***P < 0.001. Abbreviations: NC1, Inhibitor negative control 1; RE, relative expression