Fig. 2.

Dot plots of methylation (β-value) between JPA and EUA for the top ten significantly differentially methylated CpGs by P-value. All have P-value < 1.5e − 11 (FDR < 0.1). Blue points indicate EUA (n = 28), and red points indicate JPA (n = 30). Δβ is defined as average methylation in JPA—average methylation in EUA. Δβ > 0 corresponds to hypermethylation in JPA relative to EUA, while Δβ < 0 corresponds to hypermethylation in EUA relative to JPA