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. 2021 Oct 12;35(6):749–764. doi: 10.1007/s40259-021-00498-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 5 — Distribution of infliximab (A), adalimumab (B), and etanercept (C) originator/biosimilar use in the years 2015–2019, stratified by region and calendar year, and total number of users of those individual biological drugs, stratified by originator/biosimilar use (D). Biosimilar users: one or more dispensing of biosimilar only; originator users: one or more dispensing of originator only; originator + biosimilar users: one or more dispensing of biosimilar and one or more dispensing of originator