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. 2021 Sep 23;13(19):4745. doi: 10.3390/cancers13194745

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Experimentally validated targets of differentially expressed miRNAs (DEmiRs) of the comparison between tumoral x non-neoplastic tissues. (A,B) The miRTarBase 8.0 database supported information for networks representing miRNA and their experimentally validated target genes with weak and strong evidence levels for downregulated (A) or upregulated (B) DEmiRs; (C,D) Enrichment plots of Reactome pathways for experimentally validated miRNA targets with weak and strong evidence levels for downregulated (C) or upregulated (D) DEmiRs obtained from the Mienturnet tool. Each enrichment plot includes dots indicating miRNAs whose targets participate in the corresponding pathway. These dots are colored by p-adjusted value and sized by the gene ratio per pathway.