Table 1.
Clinical and histopathological characteristics of PeC patients for each set of samples.
| Patients | Total Sample n (%) |
Microarray Sample n (%) |
Validation Sample n (%) |
|---|---|---|---|
| Number of patients | 24 | 11 | 13 |
| Age at surgery-Mean (SD) years old | 61.8 (16.1) | 61.6 (14.2) | 61.9 (18.2) |
| Follow up-Median (range) months | 39.8 (2–68) | 47.5 (8–62) | 34.9 (2–61) |
| Smoking history | 14 (58.3) | 8 (72.7) | 6 (46.1) |
| cT | |||
| cT1 | 3 (12.5) | 2 (18.2) | 1 (7.7) |
| cT2 | 13 (5.2) | 4 (36.4) | 9 (69.2) |
| cT3 | 8 (33.3) | 5 (45.4) | 3 (23.1) |
| cN | |||
| cN0 | 9 (37.5) | 5 (45.4) | 4 (30.8) |
| cN1 | 8 (33.3) | 3 (27.3) | 5 (38.4) |
| cN2 | 4 (16.7) | 3 (27.3) | 1 (7.7) |
| cN3 | 3 (12.5) | 0 (0) | 3 (23.1) |
| Penectomy | |||
| Partial | 17 (70.8) | 7 (63.6) | 10 (76.9) |
| Total | 7 (29.2) | 4 (36.4) | 3 (23.1) |
| Grade | |||
| I | 3 (12.5) | 2 (18.2) | 1 (7.7) |
| II | 13 (54.2) | 6 (54.5) | 7 (53.9) |
| III | 8 (33.3) | 3 (27.3) | 5 (38.4) |
| T Stage | |||
| pT1 | 4 (16.6) | 3 (27.2) | 1 (7.7) |
| pT2 | 13 (54.2) | 4 (36.4) | 9 (69.2) |
| pT3 | 7 (29.2) | 4 (36.4) | 3 (23.1) |
| Inguinal Lymphadenectomy | 16 (66.7) | 7 (63.6) | 9 (69.2) |
| Pelvic Lymphadenectomy | 4 (16.7) | 2 (18.1) | 2 (15.4) |
| Lymph node metastasis | 12 (50.0) | 6 (54.5) | 6 (46.2) |
| Presence of HPV infection | 8 (33.3) | 3 (27.3) | 5 (38.4) |
| Tumor Size-Mean (SD) cm | 4.75 (2.27) | 4.93 (2.50) | 4.59 (2.15) |
| Lymphovascular invasion | 6 (25.0) | 3 (27.3) | 3 (23.1) |
| Perineural invasion | 10 (41.7) | 4 (36.4) | 6 (46.2) |
| Group Risk (EAU) | |||
| Low | 1 (4.2) | 1 (9.1) | 0 (0) |
| Intermediate | 3 (12.5) | 2 (18. 2) | 1 (7.7) |
| High | 20 (83.3) | 8 (72.7) | 12 (92.3) |
PeC: penile cancer; n: number of individuals; SD: standard deviation; HPV: human papillomavirus; EAU: European Association of Urology.