Table 4.

DEGs detected in the comparison of tumor tissues (n = 24) and non-neoplastic tissues (n = 24) of PeC patients by qRT-PCR.

Reg	DEG	FC	FDR	DEG	FC	FDR	DEG	FC	FDR
Down	ABCB1	0.24	<0.001 *	LATS2	0.58	0.004 *	RIPK3	0.53	<0.001 *
	ALDH1A1	0.09	<0.001 *	MDM2	0.71	0.003 *	SAV1	0.45	<0.001 *
	BCL2	0.31	<0.001 *	MLH1	0.77	0.007 *	STAT3	0.66	<0.001 *
	CCND1	0.61	0.007 *	NANOG	0.33	0.005 *	STK4	0.65	0.002 *
	EGR1	0.19	<0.001 *	NRP1	0.48	<0.001 *	TCF7L2	0.36	<0.001 *
	FGF2	0.18	<0.001 *	PEBP1	0.53	<0.001 *	TLR4	0.28	<0.001 *
	FOS	0.18	<0.001 *	PITX2	0.30	<0.001 *	TP53	0.57	0.003 *
	HOXA9	0.51	0.003 *	PPARGC1A	0.11	<0.001 *	TWIST1	0.18	<0.001 *
	KAT6A	0.47	<0.001 *	PTEN	0.55	<0.001 *	ZEB1	0.23	<0.001 *
	KLF4	0.22	<0.001 *	RECK	0.24	<0.001 *
	KMT2A	0.40	<0.001 *	RHOA	0.66	<0.001 *
Up	IL1A	13.39	<0.001 *	MMP1	28.00	<0.001 *	SFN	4.26	0.004 *
	MCM2	2.14	<0.001 *	MMP12	9.97	<0.001 *	VEGFA	2.06	<0.001 *

DEGs: differentially expressed genes; n: number of individuals; PeC: penile cancer; Reg: regulation; FC: fold change; FDR: false discovery rate; qRT-PCR: quantitative Reverse Transcription Polymerase Chain Reaction; * p < 0.05.