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. 2021 Oct 12;2021(10):CD012723. doi: 10.1002/14651858.CD012723.pub2

Comparison 8. Laser plus sclerotherapy (polidocanol) versus sclerotherapy (polidocanol).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
8.1 Resolution or improvement of telangiectasias 2 710 Std. Mean Difference (IV, Random, 95% CI) 5.68 [5.14, 6.23]
8.2 Adverse events 2   Risk Ratio (M‐H, Random, 95% CI) Subtotals only
8.2.1 Hyperpigmentation 2 656 Risk Ratio (M‐H, Random, 95% CI) 0.83 [0.35, 1.99]
8.2.2 Matting 2 656 Risk Ratio (M‐H, Random, 95% CI) 0.83 [0.21, 3.28]
8.3 Pain 1   Risk Ratio (M‐H, Random, 95% CI) Totals not selected