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. 2021 Sep 22;18(19):9952. doi: 10.3390/ijerph18199952

Table 2.

Primary Outcomes.

References Title Year Type of Substance Measurement used for Assessment Intervention Effect on Substance Use Odds Ratio Confidence Interval p-Value Quality Assessment Rating
Bullock, L., et al. [36] Baby BEEP: A Randomized Controlled Trial of Nurses’ Individualized Social Support for Poor Rural Pregnant Smokers 2009 Smoking Readiness to Stop Smoking,
The Fagerstrom Test for Nicotine Dependence and Dosage (cotinine < 30ng/mL)
The nurse-delivered social support telephone intervention was not more effective than booklets alone or usual care in reducing smoking behaviour. 1.18 0.90–1.54 0.239 3
Naughton, F. [41] Large multi-centre pilot randomized controlled trial testing a low-cost, tailored, self-help smoking cessation text message intervention for pregnant smokers (MiQuit) 2017 Smoking Validated 4-week continuous abstinence (CO readings < 9ppm),
Self-reported 4-week continuous abstinence,
7-day point prevalence for 4-weeks continuous abstinence
No statistical significance was found between the MiQuit intervention group and the usual care control group. 1.32 0.68–2.56 0.409 1
Herbec, A., et al. [42] Pilot randomized controlled trial of an internet-based smoking cessation intervention for pregnant smokers (‘MumsQuit’) 2014 Smoking Self-reported 4-week continuous abstinence The analysis determined no significant difference when measuring continuous abstinence rates between the MumsQuit intervention and control group. 1.50 0.79–2.86 0.217 1
Ondersma, S. J., et al. [43] Computer-Delivered Screening and Brief Intervention for Alcohol Use in Pregnancy: A Pilot Randomized Trail 2015 Alcohol Use Self-reported 90-day abstinence period No statistical significance was found between the intervention group and the control group when comparing abstinence. 3.20 0.52–19.78 0.211 0
Tzilos, Wernette. G., et al. [44] A Pilot Randomized Controlled Trial of a Computer-Delivered Brief Intervention for Substance Use and Risky Sex During Pregnancy 2018 General substance use Self-reported substance use behaviours using a calendar and multiple prompts The final analysis determined no significant reduction of substance use in the intervention group compared to the control group. 2.06 0.59–7.31 0.249 2
van de Wulp, N., et al. [45] Reducing Alcohol Use During Pregnancy Via Health Counseling by Midwives and Internet-Based Computer-Tailored Feedback: A Cluster Randomized Trial 2014 Alcohol Average alcohol consumption during pregnancy was assessed with the 5-item Dutch Quantity-Frequency-Variability (QFV)
Questionnaire
The final analysis showed that computer-tailoring respondents used alcohol significantly less often when compared to usual care respondents. 2.77 1.05–7.32 0.040 2