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. 2021 Sep 28;13(19):4862. doi: 10.3390/cancers13194862

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Kaplan–Meier plots of 22 mCRC cases receiving second- or later-line treatment stratified by presence of EMT CTCs. (A) Analysis of progression-free survival (PFS), (B) overall survival (OS). Patient receiving second- or later-line of treatment were grouped based on the presence and number of EMT CTCs. Patients who only had detectable EMT CTCs and 2 or more CTCs were categorized as “EMT (CTC ≥ 2)”. ‘Others’ indicates patients with <2 EMT CTCs or no detectable CTCs. p-values were calculated with the Generalized Wilcoxon test and are shown in the graph.