Table 1.
Irradiation parameters for healthy and GBM-bearing animals. The sacrifice day column is referred to the GBM-bearing groups. The sacrifice day for healthy animals was set to D138. * D26, 41 and 61 where fixed as sacrifice points to study the tumor and microcalcifications evolution.
| RT Group | Peak Dose (Gy) | Valley Dose (Gy) | Beam Width (μm) | c-t-c Distance (μm) | Sacrifice Day for GBM-Bearing Animals |
|---|---|---|---|---|---|
| BB5 | 5 | -- | -- | -- | 20–23 |
| BB10 | 10 | -- | -- | -- | 29–38 |
| BB15 | 15 | -- | -- | -- | 42–44 |
| MRT200 | 200 | 7.7 | 50 | 200 | 15–31 |
| MRT400 | 400 | 15.3 | 50 | 200 | 43–59 |
| MRT600 | 600 | 23.0 | 50 | 200 | 26, 41, 61, 55–138 * |
| MB180 | 180 | 7.2 | 500 | 1000 | 26–30 |
| MB350 | 350 | 14.0 | 500 | 1000 | 15–16 |
| Controls | -- | -- | -- | -- | 20–26 |