Figure 3.

Tumour microbial subtypes. Hierarchical clustering of tumours (Aitchinson distance) and genera (Euclidean distance) based on the clr-transformed abundances of 57 tumour genera. Clinical variables of individual patients are shown. Proportions right to the genera name denote incidence of the genus in 178 tumour-mucosa samples. (TMS—tumour microbial subtypes, clr—centered log—ratio transformation, pT—tumour pathologic stage, pN—regional lymph nodes pathologic, M—synchronous distant metastasis, Tis—tumour in situ).