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. 2021 Sep 28;13(19):4843. doi: 10.3390/cancers13194843

Table 1.

Summarized characteristics of reviewed studies.

Total 23 Studies
Year of publication 1985–2021
Number of patients
PVL 543
Developing oral cancer 288
Number of tumors 504
Sample size, range
PVL 3–81
Developing oral cancer 1–48
Number of tumors 1–130
Study design
Retrospective longitudinal 23 studies
Prospective longitudinal 1 studies
Follow up periods
Mean of means 65.63 months
Range 14–174
Geographical region
Europe 9 studies, 4 countries: France, Italy, Spain, UK
North America 9 studies, 1 country: USA
Asia 3 studies, 3 countries: India, Israel, Malaysia
South America 1 study, 1 country: Brazil
Multicontinent 1 study, 2 countries: Brazil-USA
Total 4 continents (9 countries)

Table S1 (Supplementary Materials, pp. 3–5) exhibits in more detail the characteristics of each study.