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. 2021 Oct 8;13(19):5030. doi: 10.3390/cancers13195030

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Univariable survival analyses according to molecular markers (a,b), smoking habits (c), and histotype (d). (a) Outcome (disease-specific survival) of IDH2-mutated (n = 5), INI1 negative (n = 9), and IDH2/INI1 wild-type (n = 37) cases; (b) Outcome of IDH2-mutated, INI-1 negative or LINE-1 hypermethylated cases combined together (presence of at least one variable, n = 27) versus wild-type or LINE-1 < 70% cases (n = 24); (c) outcome of smokers (n = 22) versus non-smokers (n = 29); (d) disease-specific survival analysis comparing the three histotypes: NEC (neuroendocrine carcinomas), SCC (squamocellular carcinoma), and SNUC (sinonasal undifferentiated carcinoma).