Figure 6.

Overview on affected metabolic and immunological key pathways in macrophages due to stimulation with the AhR ligands BaP, IAld, and I3AA with or without LPS co-stimulation. Metabolic pathways like mTOR, fatty acid β-oxidation, or oxidative phosphorylation as well as immune regulatory pathways like Fcγ receptor (FcγR)-mediated phagocytosis or interferon signaling were regulated in a ligand-dependent manner.