FIG. 5.

Predicted amino acid sequence of murine Ei24 protein. The previously published sequences of murine and human Ei24/PIG8 proteins contained a frameshift mutation corresponding to codon 266 (25, 33). The corrected murine Ei24 primary amino acid sequence is presented and the site of divergence from the published sequence is indicated by the arrowhead. The open reading frame of murine Ei24 is 358 amino acids, which is 98% identical to human Ei24/PIG8 and more than 50% similar to sequences found in C. elegans. The predicted sequence lacks obvious functional motifs but does contain six putative membrane-spanning domains, which are underlined.