Table 2.

Microbiome studies in pediatric ALL patients.

Time Point	Sample Type	Patients	Controls	Time Points	Seq. Region	Refs.
At time of diagnosis	Oral	13	13	1	V1-V3	[31]
	Stool	23+5	23	4	V1-V3	[8]
	Fecal	30	33	1	V3-V4	[32]
	Stool	58	23	1	V1-V9	[33]
During therapy	Stool	36	36	patients = 3; controls = 1	N/A	[34]
	Stool	199	0	4	V1-V3	[35]
	Stool	32	25	13	V4	[36]
	Anal swabs	7	7	3	V4	[37]
	Stool	51	19	patients = 5; controls = 2	V3-V4	[38]
Complications during therapy	Stool	42 (15 ALL)	0	1	V3-V4	[12]
	Stool	199	0	4	V1-V3	[35]
	Stool	16	0	2	V4-V5	[39]
	Stool	51	19	patients = 5; controls = 2	V3-V4	[38]
	Oral	39	39	1	V1-V3	[40]
After therapy	Anal swabs	73	61	1	V4	[41]
	Stool	32	25	13	V4	[36]
	Stool	38	16	1	V4	[42]
	Anal swabs	7	7	3	V4	[37]