Table 1.

Patient characteristics.

Factor	Strata	n	%
Total		167	100
Sex	Male	84	50
	Female	83	50
Histological subtype	Undifferentiated pleomorphic sarcoma	55	33
	Leiomyosarcoma	30	18
	Synovial sarcoma	20	12
	Liposarcoma	35	21
	Angiosarcoma	5	3
	MPNST	9	5
	Other	13	8
Grading	Intermediate (G2)	84	50
	High (G3)	83	50
Location	Extremities	58	35
	Non-Extremities	109	65
Size	50–80 mm	56	33
	≥80 mm	93	56
	Missing	18	11
Surgical margins	R0	44	26
	R1	96	58
	R2 or no resection	27	16
AJCC stage	Stage II	31	18
	Stage III	118	71
	Missing	18	11
Tumor response	Complete/partial response	24	14
	Stable disease	78	47
	Progressive disease	24	14
	Missing	41	25
TOP2A expression	Low (0–9%)	88	53
	High (10–100%)	79	47
SIRT1 expression	Low (0–9%)	67	40
	High (10–100%)	100	60