ALDH1 |
Aldehyde Dehydrogenase 1 |
AKT |
Protein Kinase B |
BBB |
Blood Brain Barrier |
BC |
Breast Cancer |
BCAFs |
Breast Cancer Associated Fibroblasts |
BMPs |
Bone Morphogenetic Proteins |
CAA |
Cancer Associated Adipocyte |
CAF |
Cancer Associated Fibroblast |
CCL2 |
Chemokine C-C Motif Ligand 2 |
CCL3 |
Chemokine C-C Motif Ligand 3 |
CCL5 |
Chemokine C-C Motif Ligand 5 |
COX-2 |
Cyclooxygenase 2 |
CTCs |
Circulating Tumor Cells |
CTLA-4 |
Cytotoxic T-Lymphocyte-Associated Protein 4 |
CXCL12 |
C-X-C Motif Chemokine Ligand 12 |
DSP |
Digital Spatial Profiling |
EC |
Endothelial Cells |
ECM |
Extracellular Matrix |
EGF-1 |
Epidermal Growth Factor-1 |
EGFR |
Epidermal Growth Factor Receptor |
EMT |
Epithelial-Mesenchymal Transition |
ER |
Estrogen Receptor |
FAK |
focal adhesion kinase |
FAPα |
Fibroblast Activation Protein Alfa |
GABA |
Gamma Aminobutyric Acid |
HER2 |
Human Epidermal Growth Factor Receptor 2 |
HGF |
Hepatocyte Growth Factor |
IGF1 |
Insulin-like Growth Factor 1 |
IL-10 |
Interleukin-10 |
IL-1β |
Interleukin-1 Beta |
IL-3 |
Interleukin 3 |
IL-6 |
Interleukin-6 |
JAG1 |
Notch Ligand Jagger1 |
JAK/STAT3 |
Janus Kinase/Signal Transducer and Activator of Transcription 3 |
M1 |
Classically Activated Macrophages |
M2 |
Alternatively activated Macrophages |
MDSCs |
Myeloid Derived Suppressor Cells |
MMPs |
Matrix Metalloproteinase |
NADH |
Reduced Nicotinamide Adenine Dinucleotide |
NF-kB |
Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells |
PD-1 |
Programmed Cell Death-1 |
PDGF |
Platelet-Derived Growth Factor |
PDGFR-α |
Platelet-Derived Growth Factor Receptor A |
PD-L1 |
Programmed Cell Death-1 Ligand |
PI3K |
Phosphatidylinositol 3-Kinase |
PR |
Progesterone Receptor |
PTEN |
Phosphatase and Tensin Homolog |
RANKL |
Receptor Activator of Nuclear Factor Kappa-Β Ligand |
S100A4 |
S100 Calcium Binding Protein A4 |
scRNA-seq |
Single Cell RNA Sequencing |
STING |
Stimulator of Interferon Genes |
TAM |
Tumor Associated Macrophages |
TEC |
Tumor endothelial cells |
TGF-β1 |
Transforming Growth Factor-Beta 1 |
TME |
Tumor Microenvironment |
TNBC |
Triple-Negative Breast Cancer |
TNFRSF4 |
Tumor Necrosis Factor Receptor Superfamily, Member 4 |
TNF-α |
Tumor Necrosis Factor-Alpha |
VEGF |
Vascular Endothelial Growth Factor |
Wnt |
Wingless-related Integration Site |