Figure 4.
DEX-induced caspase-3 activation in SH-5Y5Y is attenuated by colostrum treatment. Caspase-3 activity was determined using the fluorogenic substrate Ac-DEVD-AMC. Data are expressed in fluorescence arbitrary units (FAU) and represent the mean ± S.E.M. of three independent experiments. Significant differences of 400 μM and 700 μM DEX treated cells versus the control untreated cells were found (Newman–Keuls test, * p < 0.001 vs. control). Significant differences of colostrum plus DEX treated cells versus DEX-treated cells were found (Newman–Keuls test, # p < 0.05 vs. DEX treated cells).