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CD147 modulates lymphangiogenic properties of LECs. LECs were treated with or without rhCD147, or with a positive control mix (VEGF-A + bFGF + VEGF-C) and evaluated for effects on cell migration (a), proliferation (b), apoptosis (c), and tubulogenesis (d). Columns indicate the means of three independent experiments carried out in triplicate and bars indicate the SD; ** p < 0.005, *** p < 0.0001.
