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. 2021 Oct 1;13(19):4964. doi: 10.3390/cancers13194964

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Prognostic baseline levels of circulating lipids for Cohort 1 and Cohort 2a: (a) Kaplan–Meier curves of the association of the poor prognostic 3-lipid signature (3LS) at baseline with OS. The 3LS consists of Cer(d18:1/24:1), SM(d18:2/16:0), and PC(16:0/16:0); (b) Forest plots of hazard ratios of OS for baseline plasma levels of lipids in both cohorts; (c) Forest plot of hazard ratios of rPFS for baseline plasma levels of lipids significantly associated with rPFS and OS in Cohort 2a.

Prognostic baseline levels of circulating lipids for Cohort 1 and Cohort 2a: (a) Kaplan–Meier curves of the association of the poor prognostic 3-lipid signature (3LS) at baseline with OS. The 3LS consists of Cer(d18:1/24:1), SM(d18:2/16:0), and PC(16:0/16:0); (b) Forest plots of hazard ratios of OS for baseline plasma levels of lipids in both cohorts; (c) Forest plot of hazard ratios of rPFS for baseline plasma levels of lipids significantly associated with rPFS and OS in Cohort 2a.