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. 2021 Sep 30;13(19):4948. doi: 10.3390/cancers13194948

Table 3.

Light therapy characteristics *.

Characteristic No. (%) a p N
All Survivors BWL (n = 83) DWL (n = 83)
Season LT start 0.94 164
Autumn 42 (25.6) 23 (27.7) 19 (23.5)
Winter 47 (28.7) 23 (27.7) 24 (29.6)
Spring 47 (28.7) 23 (27.7) 24 (29.6)
Summer 28 (17.1) 14 (16.9) 14 (17.3)
LT device
Litebook Edge 37 (22.6) 18 (21.7) 19 (23.5) 164
Luminette 127 (77.4) 65 (78.3) 62 (76.5) 164
Days of LT use based on LT diary b 0.52 155
Mean 22.7 22.5 22.9
SD 4.4 4.6 4.0
>25 days c 3 (1.9) 0 (0.0) 3 (3.9) 0.13 155
25 days 58 (37.4) 33 (41.8) 25 (32.9)
14–24 days 87 (56.1) 41 (51.9) 46 (60.5)
1–13 days (premature stop) 7 (4.5) 5 (6.3) 2 (2.6)
Time difference sleep end and LT start (min) d 0.13 155
Mean 25.0 27.4 22.6
SD 19.5 22.6 15.3
Time difference DLMO and LT start (h) 0.17 45
Mean 11.4 11.1 11.7
SD 1.5 1.0 1.9
n 45 23 22
Self-reported side effects
Headache/nausea 35 (21.6) 21 (25.6) 14 (17.5) 0.21 162
Feeling agitated b 5 (3.1) 1 (1.2) 4 (5.0) 0.21 162
Tired eyes 30 (18.5) 11 (13.4) 19 (23.8) 0.09 162
Change in vision b 8 (4.9) 5 (6.1) 3 (3.8) 0.72 162
Other self-reported side effects e 15 (9.3) 6 (7.3) 9 (11.3) 0.39 162
Premature stop of LT 13 (7.8) 7 (8.4) 6 (7.2) 0.77 166
Reasons for premature stop b 0.21 13
Self-reported side effects 7 (53.8) 5 (71.4) 2 (33.3)
No time or personal circumstances 6 (46.2) 2 (28.6) 4 (66.7)

Note: shading in the table represents the distinction between variables. * Two participants never started with light therapy and therefore characteristics of light therapy are reported for 164 participants. Light therapy diaries were completed by 155 participants. DLMO was determined for 45 participants. In total, 162 participants completed the screening on side effects during a telephone call. Abbreviations: BWL, bright white light; DLMO, dim light melatonin onset; DWL, dim white light; LT, light therapy. a Unless otherwise specified. b Categorical test results is based on Fisher’s Exact Test. c Some individuals misinterpreted the study protocol and used light therapy for 28, 30, or 33 days. d Based on Mann–Whitney Test. e Other self-reported side effects included worse sleep quality (n = 7), feeling more fatigued (n = 2), feeling rushed (n = 1), shingles (n = 1), feeling confused (n = 1), sensitive gingiva (n = 1), and a dry mouth (n = 1).