Table 2.
Hazard ratios (HRs) and 95% confidence intervals (CIs) comparing survival outcomes on second-line (2L) docetaxel vs. 2L alternate NHT. The HRs are from Cox proportional hazards models weighted using matching weights from propensity scores to adjust for potential confounding.
| 1L Therapy | Outcome | 2L Therapy | N | HR (95% CI) | p |
|---|---|---|---|---|---|
| Abiraterone | TTTTD | Enzalutamide | 508 | 1.00 (ref) | |
| Docetaxel | 187 | 1.26 (1.04, 1.53) | 0.018 | ||
| OS | Enzalutamide | 508 | 1.00 (ref) | ||
| Docetaxel | 187 | 1.32 (1.07, 1.64) | 0.009 | ||
| Enzalutamide | TTTTD | Abiraterone | 290 | 1.00 (ref) | |
| Docetaxel | 132 | 1.36 (1.09, 1.70) | 0.008 | ||
| OS | Abiraterone | 290 | 1.00 (ref) | ||
| Docetaxel | 132 | 1.40 (1.09, 1.80) | 0.009 |