Table 4.
E-cigarette use and subsequent smoking cessation in randomized controlled trials
| Association with smoking cessation | Participants | Number of studies | Risk difference | Odds ratio | Certainty of evidence | Down rating |
|---|---|---|---|---|---|---|
| RD (95% CI)* | OR (95% CI) | |||||
| Full material | 3203 | 8** | 0.07 (0.03–0.12) | 1.78 (1.41–2.25) | Low (⊕⊕) | -1 risk of biasa -1 inconsistencyb |
| Short follow-up (≤6 months) | 3203 | 8** | 0.06 (0.02–0.10) | 1.67 (1.32–2.11) | Low (⊕⊕) | -1 risk of biasa -1 inconsistencyb |
| Long follow-up (>6 months) | 884 | 1 | 0.09 (0.04–0.14) | 2.00 (1.38–2.89) | Low (⊕⊕) | -1 risk of biasa -1 material with several limitationsc,d |
| <18 years | Not available | |||||
| ≥18 years | 3203 | 8** | 0.07 (0.03–0.12) | 1.78 (1.41–2.25) | Low (⊕⊕) | -1 risk of biasa -1 inconsistencyb |
| Women | Not available | |||||
| Men | 150 | 1** | Not available | Not available | Low (⊕⊕) | -1 risk of biasa -1 material with several limitationsc,d |
*
Calculated from unadjusted values.
**
One study was included narratively. Outcome: 7-day point prevalence of abstinence after 24 weeks. Among participants allocated nicotine gum 29.3% were abstinent, and 22.7% among those allocated e-cigarettes. No statistically significant difference between groups.
a
Material with several deficits and limitations.
b
The confidence intervals of individual studies include 1.0, indicating no statistically significant association.
c
The analysis is based on a limited number of studies.
d
The analysis is based on few participants.