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. 2021 Oct 5;13(19):4999. doi: 10.3390/cancers13194999

Figure 2.

Figure 2

Kinetics of the response of NF-Y-dependent cell proliferation to acute ethanol administration in the MITO-Luc mouse model. Longitudinal BLI imaging performed at different time points after administration on MITO-Luc mice administered with either vehicle (saline) or ethanol solution. Luciferase emission was determined by BLI in (a) a representative animal and (b) in each acquisition, regions of interests countering the whole animal were delineated and BLI emission quantified using the Living Image software. The graph illustrates BLI signal intensities relative to saline control levels set as 100%. (c) MITO-Luc mice were administered with either vehicle or C2H6O solution; after 8 weeks of recovery, the administration was repeated at the same dose. Quantification of the BLI signals was performed 1 week after each administration The pseudo-color scale bar indicates the relative signal intensity from the lowest (blue) to the highest (red) (range 1 × 104–1 × 105 photons/s/cm2/sr). The asterisk (*) indicates a statistically significant difference compared with the relative saline group.