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Ex vivo assays for the first pharmacological screening of the compounds. (A) Compounds that showed potential to downregulate the TNF induced cytotoxicity on L929 cells. (B) Compounds that were ineffective in downregulating the TNF induced cytotoxicity on L929 cells were excluded from further analysis. (C) Cytotoxicity of the effective compounds on L929 cells. All error bars indicate SEM values. (D) Conclusive table of the IC50 values of A and LC50 values of (C).
