Table 2.
Analysis | Univariate | Multivariate | |||||
---|---|---|---|---|---|---|---|
Covariate | Cut-Off | HR | 95% CI | p-Value | HR | 95% CI | p-Value |
CALLY | <1 point | 1.9 | 1.4–2.6 | <0.001 | 1.5 | 1.1–2.1 | 0.008 |
Age | ≥70 years | 1.0 | 0.8–1.3 | 0.960 | |||
AFP | >400 ng/mL | 0.9 | 0.7–1.2 | 0.620 | |||
Bilirubin level | ≥1.2 mg/dL | 2.1 | 1.6–2.7 | <0.001 | 1.8 | 1.4–2.5 | <0.001 |
AST level | >31 U/L | 2.0 | 1.1–3.7 | 0.025 | 2.0 | 1.1–3.6 | 0.033 |
ALT level | ≥35 U/L | 1.2 | 0.9–1.6 | 0.200 | |||
INR level | >1.2 | 1.1 | 0.8–1.5 | 0.460 | |||
Platelet count | >150/nL | 1.3 | 0.9–1.7 | 0.140 | |||
Tumor number | ≥2 | 1.5 | 1.0–2.1 | 0.027 | 1.2 | 0.8–1.6 | 0.388 |
Max. lesion size | >5.0 cm | 1.3 | 1.0–1.7 | 0.058 |
AFP, alpha fetoprotein. AST, aspartate aminotransferase. ALT, alanine aminotransferase.