Table 3.

Univariate and multivariate analysis results for patients classified as BCLC B.

Analysis		Univariate			Multivariate
Covariate	Cut-off	HR	95% CI	p-Value	HR	95% CI	p-Value
CALLY	<1 point	1.9	1.3–2.9	0.002	1.5	1.1–2.1	0.010
Age	≥70 years	1.0	0.7–1.5	0.930
AFP	>400 ng/mL	1.0	0.7–1.4	0.790
Bilirubin level	≥1.2 mg/dL	1.9	1.3–2.8	<0.001	1.9	1.4–2.5	<0.001
AST level	>31 U/L	1.5	0.7–2.9	0.280
ALT level	≥35 U/L	1.3	0.9–1.9	0.230
INR level	>1.2	1.1	0.7–1.6	0.770
Platelet count	>150/nL	1.1	0.7–1.7	0.720
Max. lesion size	>5.0 cm	1.5	1.0–2.3	0.035	1.3	1.0–1.7	0.069

AFP, alpha fetoprotein. AST, aspartate aminotransferase. ALT, alanine aminotransferase.