Table 5.
Comparison of the CALLY index to existing immunonutritive and inflammation indices.
| Score | Median OS | HR | 95% CI | p-Value | C-Index | |
|---|---|---|---|---|---|---|
| All Patients (n = 280) | ||||||
| CALLY | ≥1 | 24.0 | Reference | 0.60 | ||
| <1 | 9.0 | 1.9 | 1.4–2.6 | <0.001 | ||
| NLR | ≤3 | 16.5 | Reference | 0.59 | ||
| >3 | 7.6 | 1.8 | 1.4–2.4 | <0.001 | ||
| PLR | <164 | 12.8 | Reference | 0.54 | ||
| ≥164 | 10.2 | 1.3 | 1.0–1.8 | 0.082 | ||
| PNI | >36 | 18.8 | Reference | 0.63 | ||
| ≤36 | 6.5 | 2.4 | 1.8–3.2 | <0.001 | ||
| SII | <664 | 13.8 | Reference | 0.56 | ||
| ≥664 | 8.6 | 1.5 | 1.1–2.1 | 0.006 | ||
| ILIS | <11 | 18.8 | Reference | 0.57 | ||
| ≥11 | 10.2 | 1.5 | 1.3–2.5 | <0.001 | ||
| BLCL B subgroup (n = 164) | ||||||
| CALLY | ≥1 | 26.2 | Reference | 0.61 | ||
| <1 | 13.1 | 1.9 | 1.3–2.9 | 0.002 | ||
| NLR | ≤3 | 18.3 | Reference | 0.59 | ||
| >3 | 9.0 | 2.5 | 1.6–3.8 | <0.001 | ||
| PLR | <214 | 16.5 | Reference | 0.55 | ||
| ≥214 | 7.5 | 2.5 | 1.4–4.4 | 0.002 | ||
| PNI | >39 | 20.9 | Reference | 0.63 | ||
| ≤39 | 10.3 | 1.9 | 1.3–2.8 | <0.001 | ||
| SII | <622 | 16.7 | Reference | 0.55 | ||
| ≥622 | 10.0 | 1.9 | 1.2–3.1 | 0.007 | ||
| ILIS | <31 | 17.9 | Reference | 0.58 | ||
| ≥31 | 10.4 | 2.0 | 1.4–3.0 | <0.001 | ||
NLR, neutrophil-to-lymphocyte ratio. PLR, platelet-to-lymphocyte ratio. SII, systemic immune-inflammation index. ILIS, integrated liver inflammatory score. PNI, prognostic nutritional index.