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Schema illustrating the experimental design and data analyses. (A) Plasma exosomes were isolated and purified from obstructive sleep apnea (OSA) patients either before CPAP treatment (OSA-V1) or after treatment (OSA-V2). (B) Diagram illustrating cell culture exposed to normoxia and IH for 48 h, and exosomes characterization, exosomal miRNAs microarrays profiling, Gene Ontology and KEGG pathways.
