Table 4.
Exosomes derived from melanoma 1424, and 1675 cells exposed to normoxia and intermittent hypoxia and applied into THP1 macrophages.
| Cell Type | Genes | M1 Markers | Genes | M2 Markers | ||||
|---|---|---|---|---|---|---|---|---|
| Normoxia | Hypoxia | p-Value | Normoxia | Hypoxia | p-Value | |||
| Exosomes from 1424 cells on macrophages | CCR7 | 1 | 1.11 ± 0.012 | 0.121 | CD206 | 1 | 1.02 ± 0.01 | 0.091 |
| CXCL10 | 1 | 1.53 ± 0.016 | 0.001 | CD163 | 1 | 0.98 ± 0.07 | 0.131 | |
| IL6 | 1 | 0.93 ± 0.06 | 0.071 | IL10 | 1 | 0.91 ± 0.08 | 0.082 | |
| Cell Type | Genes | M1 Markers | Genes | M2 Markers | ||||
| Normoxia | Hypoxia | p-Value | RA | IH | p-Value | |||
| Exosomes from 1675 cells on macrophages | CCR7 | 1 | 1.26 ± 0.016 | 0.042 | CD206 | 1 | 1.01 ± 0.00 | 0.122 |
| CXCL10 | 1 | 1.35± 0.014 | 0.022 | CD163 | 1 | 1.06 ± 0.00 | 0.092 | |
| IL6 | 1 | 1.12 ± 0.011 | 0.061 | IL10 | 1 | 1.00 ± 0.00 | 0.211 | |