Table 4.
Variable or Category | Baseline | 12 Weeks | Relative Change, % 0–12 Weeks † |
24 Weeks | Change 0–24 Weeks |
Relative Change, % 0–24 Weeks |
p-value for Change 0–24 Weeks |
---|---|---|---|---|---|---|---|
VO2peak, mL/kg/min | 18.0 (13.7–25.3) |
21.7 (17.4–28.9) |
16 (7–28) |
22.9 (20.2–31.0) |
4.8 (3.5–10.0) |
26 (17–48) |
0.012 |
BMI, kg/m2 | 33.6 (31.7–42.8) |
31.7 (29.5–36.8) |
−9 (−17–−3) |
30.9 (28.2–37.0) |
−4.7 (−7.1–−1.0) |
−12 (−17–−3) |
0.008 |
Waist Circumference, cm | 104 (91–120) |
103 (90–114) |
−5 (−7–0) |
102 (89–109) |
−7 (−15–−2) |
−6 (−14–−2) |
0.007 |
DXA Total Mass, kg | 91.9 (77.5–116.1) |
81.8 (73.0–102.3) |
−8 (−22–−2) |
81.5 (68.9–97.7) |
−11.8 (−21.6–−2.2) |
−12 (−19–−3) |
0.008 |
Lean Mass, kg | 43.1 (36.6–54.3) |
43.0 (37.6–55.5) |
−3 (−5–3) |
43.6 (36.9–52.9) |
−1.4 (−2.8–0.9) |
−3 (−6–2) |
0.066 |
Fat Mass, kg | 49.3 (38.7–62.5) |
40.1 (32.5–53.9) |
−14 (−19–−8) |
39.5 (29.3–47.8) |
−9.6 (−14.8–−2.5) |
−20 (−24–−6) |
0.008 |
Fat Mass Index, kg/m2 | 17.6 (15.5–23.0) |
14.6 (13.1–19.8) |
−14 (−19–−8) |
14.8 (11.8–17.5) |
−3.7 (−5.4–−1.0) |
−20 (−24–−6) |
0.008 |
Visceral Fat Tissue, kg | 1.64 (0.98–2.92) |
1.32 (0.77–2.50) |
−19 (−35–−1) |
1.26 (0.73–2.07) |
−0.54 (−0.85–−0.16) |
−29 (−43–−11) |
0.008 |
† All comparisons of 12 week to baseline values for the subset of 9 participants are statistically significant (p-value range 0.003 to 0.041).