Table 3.
RNA-Seq data analysis among different ADSC cell line/medium formulations. A comparison between different formulations showing the presence of smooth muscle-specific long-coding RNA (lncRNA) and micro RNA (miRNA) in PT treated samples, compared to samples cultured in CCM.
| Gene Name | Significance | Expression Log Ratio | Result | |
|---|---|---|---|---|
| A2PT vs. A2CC | actin alpha 2 (ACTA2) | Expressed in smooth muscle and aids in vascular contraction | 3.758 | Increased expression in A2PT |
| miR-17-5p | Mesenchymal stem cell differentiation | 2.130 | ||
| miR-145-5p | Vascular smooth muscle cell differentiation | 3.682 | ||
| A1PT vs. A1CC | transgelin (TAGLN) | Expressed in vascular and smooth muscles and is an early marker of smooth muscle differentiation. | 3.272 | Increased expression in A1PT |
| A2PT vs. A1PT | actin alpha 2 (ACTA2) | Expressed in smooth muscles and aids in vascular contraction | 3.044 | Increased Expression in A2PT Decreased Expression in A2PT |
| miR-21-5p | Adipose mesenchymal stem cell differentiation | −3.523 |