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Effects of EVs on canonical cardio-protective pathways. (A) Representative Western blot analysis and histograms of cells subjected to H/R protocol, after EV treatment (n = 30). (B) Representative Western blot analysis and histograms of myocardial tissues subjected to I/R protocol, after EV treatment (n = 30). p-Erk-1/2, p-STAT-3 and Bcl-2 expression were normalized to vinculin (** p = 0.002).
