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. 2021 Sep 29;22(19):10545. doi: 10.3390/ijms221910545

Table 1.

Chemical structures of PPARα endogenous agonists, synthetic agonists used in experimental studies, clinically used pharmacological agonists, and synthetic antagonists, including examples of novel N-phenylsulfonylamide compounds (the structures of 3- and 10- series according to [64]).

PPARα Agonists and Antagonists
Natural agonists graphic file with name ijms-22-10545-i001.jpg
Synthetic agonists graphic file with name ijms-22-10545-i002.jpg
Agonists applied in clinic: fibrate derivatives graphic file with name ijms-22-10545-i003.jpg
Synthetic antagonists graphic file with name ijms-22-10545-i004.jpg