Composite neuroscore in rats treated with vehicle or SFN+NAC duotherapy. The TBI-VEH group showed impairment on day (D) 2 and D6 post-injury and the TBI-DUO group showed impairment on all testing days till D13 post-TBI. No difference was detected between Sham-VEH and Sham-DUO or TBI-VEH and TBI-DUO groups at any time-point (p > 0.05). Abbreviations: D, day; DUO, duotherapy treated with N-acetylcysteine and sulforaphane; NAC, N-acetylcysteine; SFN, sulforaphane; TBI, traumatic brain injury; VEH, vehicle. Statistical significances: ** p < 0.01, *** p < 0.001 (Sham-VEH vs. TBI-VEH, Mann–Whitney U-test); ## p < 0.01, ### p < 0.001 (Sham-DUO vs. TBI-DUO, Mann–Whitney U-test). Data are presented mean ± SEM.